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The development of new drugs involves the identification
and the evaluation of new/ and current anti-viral compounds based on
their activity against a range of viruses with specific mutational
patterns compared with the activity of other drugs in the same class.
VIRalliance through its robust assay PHENOSCRIPT™ and its experienced
team can provide all the tools and expertise for measuring antiviral
drug resistance and other viral characteristics relevant to the development
of drugs and vaccines for HIV-1. The evaluation of new agents can be
realised at all stages of drug development – pre-clinical, clinical
development, post-marketing studies and trend surveys.
PHENOSCRIPT™ is a robust and reliable assay that provides a direct
measure of the level of drug susceptibility of a virus and can identify
the most effective molecules to suppress viral replication. It can
be used to study the evolution of the comportment of a virus in presence
of a new inhibitor. A large collection of clinical and laboratory specimens
can be used to evaluate the efficacy of new drugs.
PHENOSCRIPT™ is relatively easy and rapid to perform and the
interpretation of results, the reproducibility, sensitivity, and accuracy
of the assay have all been fully validated.
The highest level of service is provided by a reliable technological
platform, which is fully certified with an international accreditation
(ISO9001:2002 ).
Through its numerous partnerships with academic centres and other companies,
VIRalliance can provide a full testing service including phenotypic
and genotypic resistance tests, viral fitness assessments, HIV serology
and logistic services. Our research and development team is constantly
working to improve PHENOSCRIPT™ and to develop new assays and
technologies.
The service provided is delivered from a knowledgeable and experienced
team. Our staff has extensive expertise in virology, molecular biology,
assay development and clinical research, which enables us to provide
the highest quality of service. World-renowned opinion leaders such
as Francois Clavel are part of our scientific advisory board.
Our team has the experience to assist at all stages of your research
and development projects including design, data analysis, presentation,
and publication. Clinical support such as patient selection for clinical
trials can also be organised.
Customer satisfaction and quality of results are our main objectives.
Our aim is to provide optimal transparency regarding our work and our
results, making our customer service exceptional.
Principle
of the PHENOSCRIPT™ assay
The PHENOSCRIPT™ report
Important
parameters
Comparison
with other commercially available tests
To order PHENOSCRIPT™
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